Smoke Choked

Formerly known as Custom Photo Dojo, this is a M.U.G.E.N. game based on the DSiWare game of the same name.  Here, you can play as various pop culture characters, from Nintendo characters, to indie game characters, to anime characters, to YouTubers.  While some characters share similar movesets, a good amount of the game is diversified with various playstyles.
By MrBastMugen
 

Yet obscenely cheap JUS edit
Take a good guess where this came from
By The Kingdom of NEGUM
 

The proud Devildom aristocrat from the depths of Hell has been summoned to bring ultimate destruction to the world.
Give your worthless opponents the death penalty by unleashing Jashin-chan's mighty dropkicks, now in MUGEN!
Okay, not really.
This is a joke voice patch for OHMSBY's Susanoo that uses voice clips of Jashin-chan from Jashin-chan Doropukkiku / Dropkick on My Devil
Most sounds are taken from season 3 but some are taken from season 1 and 2
How to use? very ez.
Drag and drop (or copy and paste) the def, snd and cns files to your OHMSBY Susanoo copy, and replace the same and current files and you should be ready.

An additional palette is also included, it (kinda) references Jashin-chan of course! This can be used for the original/unedited version too.
By OHMSBY, voice patch by Sergio P
 

I presume this was made for a close friend of the author, if not the romantic interest of said author. Whatever this Jenny's relationship is to Pedro, this was released for her birthday on April 19th.
By XXMarioLover64BRXX

Revisit the classic maze arcade game created by Namco!
Control the protagonist Dig Dug to eliminate all the Pookas and Fygars on the screen using an air pump to inflate them to bursting, in order to progresses to the next stage.
Watch out, as enemies chase Dig Dug through dirt in the form of ghostly eyes, only becoming solid in the air where his pump can stun or destroy them. Enemies eventually become faster and more aggressive and the last one will try to escape.
By Falonso
 

A custom Bass from Mega Man: The Power Fighters.  He lacks A.I., however.
By Argetlam

By Kazecat
 

The protagonist of the critically acclaimed Hollow Knight.  A simple 3 button character, with a fourth button for an extra move.
By Zobbes
 

The "father" of Caillou from the Vyond videos.  This guy will make sure you are grounded, grounded, grounded, grounded, grounded, grounded, grounded, grounded, grounded, grounded, grounded, grounded, grounded, grounded, grounded, grounded, grounded, grounded, grounded, grounded, grounded, grounded, grounded, grounded, grounded, grounded, grounded, grounded, grounded, grounded, grounded, grounded, grounded, grounded, grounded, grounded, grounded, grounded, grounded, grounded, grounded
By Dawn de Era
 

What don't you understand about...MORE?!
A proper version of Moar Krabs.  No longer a still image, but now is a Mr. Krabs edit that attacks with Moar Krabs projectiles.
By Warioman+Z/Edited by XXMarioLover64BRXX
 

Hey, Boyfriend!  Check out these new songs I learned in the Cyber World!
Music and charting by DeltaB
Art by AmazeinG666
Coding by wedgecuts
 

From WikiPedia, the free Encylopedia, this guy represents just how hard Where's Waldo is on the NES, according to Joel.  This guy ended up becoming the kinkiest bastard in all of The Sims 4 Meme House.  watch your back!
By Brergrsart
File 1: 1.1 version
File 2: 1.0 version
 

Surprisingly, the spyware ape serves as the final boss of Vargverse.  In addition to having hyper armor, he uses all sorts of random virus and meme attacks, though he thankfully has a notable pause between every attack.  Believe me, some of his attacks can be pretty long to endure.  Plus, he has two phases, and for at least one round, he will activate a OHKO finisher when he is at low health during his second phase.  If you do not defeat him within 30 seconds, while tons of Bonzi heads are trying to obstruct you way of attacking...it's Total Destruction.
By Brergrsart
 

The greatest of Lucario edits, and KK Hell's mascot.  He's honestly one of my favorite characters.
By KK Hell
 

Quoted from NGCM Readme:
By Z-9 Lurker
 

Squidward!  The Flying Dutchman wants to kill me!
What started as a stupid meme became a pretty interesting mod
Art by AdvideGEP
Coding by BitTech
 

A character designed for FourthRhyme Fighters.  One of the one Jennys that isn't crudely edited or spriteswapped from something else, and has some good sprite rips as well!
By AngryBirdCooler and FourthRhyme

A fallen angel of the smelliest kind
WARNING: Contains onara (fart fetish)
By Dissidia

Emilia, the waifu no one wanted from Re:Zero, done in the KOF style with original sprites!
By Light
 

Aggron, but edited from Godzilla
By fu-lin&kirbey

One of the main characters of Crimson Alive, formerly the antagonist of Genesis of The Heretic, the original installment of Crimson Alive.
By jade_midori
2nd file: AI patch by Holn
 

By Planeptune Arte
 

By Mystery107
No memes in #general
Based on this, I think? 
 

Nick Hooper, but his A.I. has a tendency to automatically activate his finisher.  He is still fully playable, but he will not act as intended when played as.
By DarkDonald1, edited by p0008874

Homer Simpson, but he spams vehicles at the start of the round, and he has endless regeneration.  Easily one of the cheapest Homers out there.
By NintendoFanGC